I have gone back and forth on PNAS over the years. Science and Nature work at an even higher level, of course, but I have a general scientific curiosity, so they work well for me. It's true that many of the papers will be on topics that you know little about (or might care for even less), but you'll see some things you wouldn't otherwise see, while also getting quality work that's relevant to your own interests. I would recommend having some of the big, general ones in there, such as JACS and Angewandte Chemie and Nature Chemistry for chemistry. A similar experience that I've never found a way to recapitulate in the digital world was the way that you'd come across other papers while looking up other references in the bound journals, but that one may be gone forever.
What I'm trying to do with RSS is to replicate the older experience of flipping through the paper journals as they came in, because I found that I came across interesting things that way that I might not have seen otherwise. There are a lot of sites that will handle feeds for you - I use one called NewsBlur, so you might start there if you're looking to get going. But I've found that RSS is congenial to the way I scan things (it may not work the same for everyone). I use an RSS reader to try to keep up, although I will freely admit that I have not been as diligent with the general literature during some of this pandemic period. A large-scale problem is what journals to even look at. So here's what I have to offer, and I hope it helps. Which is indeed a problem, on several levels, and has been for a long time now. I've requests from time to time to share some tips about dealing with the scientific literature.
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